New Drug to Treat Alzheimer’s Moving into Human Trials posted on: 02-03-2016

Advancement to treat Alzheimer’sThe race to end Alzheimer’s disease has taken a new and exciting direction, in light of the National Institutes of Health’s recent announcement that the experimental drug BPN14770 is poised to begin a clinical human trial. With less potential side effects than its precursor, rolipram, BPN14770 shows promising results in enhancing memory and cognitive performance in mice impacted by Alzheimer’s.

The first phase of the study will involve testing the safety of the drug in 48 healthy human volunteers, and based on those results, will then move into testing its effects on cognitive functioning, memory and learning abilities.

Unlike other studies currently underway focused on targeting amyloid plaques, BPN14770’s intended outcome is to enhance the biochemical pathway in the brain that’s responsible for formation of nerve synapses and memory. Ideally, the use of BPN14770 can eventually also aid in treating other neurological conditions, such as schizophrenia, Fragile X syndrome, and developmental disabilities.

We’ll continue to keep you updated on the progression of these exciting new developments in the quest to overcome the challenges of Alzheimer’s!

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